Last updated October 21, 2026. Approval line checked October 21, 2026. No compounding source date is assigned.
FDA status
Not approved
Not approved. This record is not an FDA-approved drug product. Approval, where it exists, is specific to a drug product, indication, and route.
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Evidence tier
Human Observational. The tier is the highest indexed study type. It is not a safety rating and it is not an FDA approval. Confidence score 2/5. 28 PubMed citations indexed.
Octapeptide extension of Argireline blocking SNARE complex formation more completely than hexapeptide variants; reduces depth of expression lines with topical application.
What the literature studies
Topical Anti-Wrinkle
Evidence tier
Human Observational
Compounding record
Status not verified
Status not verified. No product-specific FDA primary source is recorded for this entry. FDA approval and compounding eligibility are not verified. Research information is not evidence of FDA approval. Approval, where applicable, is specific to a drug product, indication and route. Research information is not evidence of FDA approval. Approval, where applicable, is specific to a drug product, indication and route.
Regulatory source not verified; no checked date is assigned.
Topical cosmetic ingredient; evidence limited to small industry-funded trials
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Educational only. Not medical advice. This page does not give doses or sourcing. See the medical and editorial disclaimer.