94 compounds with an evidence tier and an FDA status. Approval lines checked October 21, 2026. Compounding labels checked October 10, 2026 where a source is on file. Education only.
| Compound | Category | Application | Confidence | Evidence | FDA Status | PubMed |
|---|---|---|---|---|---|---|
| BPC-157Gut / repair | Recovery | Tissue Repair & Cytoprotection | 2/5 | Animal Only | HHS proposed 503A enforcement discretion (not final) | 544 |
| TB-500Muscle / tendon / recovery | Recovery | Cell Migration & Angiogenesis | 2/5 | Animal Only | HHS proposed 503A enforcement discretion (not final) | 1,031 |
| GHK-CuSkin / connective tissue | Longevity | Collagen Synthesis & Tissue Remodeling | 2/5 | Animal Only | Route-dependent status | 81 |
| EpithalonLongevity / cellular | Longevity | Telomerase Activation & Longevity | 3/5 | Human Observational | HHS proposed 503A enforcement discretion (not final) | 155 |
| MOTS-cMetabolism / fat / incretin | Metabolic | Metabolic Resilience & Aging | 2/5 | Animal Only | HHS proposed 503A enforcement discretion (not final) | 197 |
| SermorelinHormones / GH axis | Longevity | Growth Hormone Stimulation | 4/5 | Human RCT | Status not verified | 328 |
| IpamorelinHormones / GH axis | Recovery | Selective GH Secretagogue | 2/5 | Human Observational | Status not verified | 48 |
| CJC-1295Hormones / GH axis | Longevity | Long-Acting Growth Hormone Release | 3/5 | Human RCT | Nomination withdrawn | 27 |
| NAD+Metabolism / fat / incretin | Longevity | Cellular Energy & Longevity | 4/5 | Human RCT | Status not verified | 16,609 |
| Thymosin Alpha-1Immune / thymus | Immune | Immune Modulation & T-Cell Support | 4/5 | Human RCT | Nomination withdrawn | 856 |
| SemaglutideMetabolism / fat / incretin | GLP-1 | GLP-1 Metabolic & Weight Management | 5/5 | Human RCT | Status not verified | 8,400 |
| TirzepatideMetabolism / fat / incretin | GLP-1 | Dual GLP-1/GIP Agonist | 5/5 | Human RCT | Status not verified | 2,100 |
| RetatrutideMetabolism / fat / incretin | GLP-1 | Triple GLP-1/GIP/Glucagon Agonist | 3/5 | Human RCT | Status not verified | 180 |
| TesamorelinHormones / GH axis | Metabolic | HIV Lipodystrophy & GH Stimulation | 5/5 | Human RCT | Status not verified | 620 |
| PT-141 (Bremelanotide)Hormones / reproductive | Cognitive | Sexual Function & Arousal | 5/5 | Human RCT | Status not verified | 310 |
| IGF-1 LR3Muscle / tendon / recovery | Recovery | Muscle Hypertrophy & Growth Factor Signaling | 2/5 | Animal Only | Status not verified | 890 |
| HexarelinHormones / GH axis | Recovery | GH Release & Cardioprotection | 3/5 | Human RCT | Status not verified | 245 |
| GHRP-2Hormones / GH axis | Recovery | Growth Hormone Stimulation | 3/5 | Human RCT | 503B Category 2 / 503A Category 3 | 380 |
| GHRP-6Hormones / GH axis | Recovery | GH Release & Appetite Stimulation | 3/5 | Human Observational | 503B Category 2 / 503A Category 3 | 420 |
| MK-677 (Ibutamoren)Metabolism / fat / incretin | Longevity | Oral GH Secretagogue | 3/5 | Human RCT | Status not verified | 310 |
| AOD-9604Metabolism / fat / incretin | Metabolic | Metabolic & Fat Loss | 2/5 | Human Observational | Nomination withdrawn | 75 |
| LL-37 (Cathelicidin)Immune / thymus | Immune | Antimicrobial & Immune Defense | 2/5 | Animal Only | Nomination withdrawn | 3,200 |
| KPVGut / repair | Immune | Gut Inflammation & Immune Modulation | 2/5 | Animal Only | HHS proposed 503A enforcement discretion (not final) | 180 |
| SelankBrain / CNS | Cognitive | Anxiolytic & Cognitive Enhancement | 3/5 | Human Observational | Status not verified | 125 |
| SemaxBrain / CNS | Cognitive | Neuroprotection & Cognitive Function | 3/5 | Human Observational | HHS proposed 503A enforcement discretion (not final) | 165 |
| DSIPBrain / CNS | Cognitive | Sleep Regulation & Stress Response | 2/5 | Human Observational | Nomination withdrawn | 340 |
| DihexaBrain / CNS | Cognitive | Cognitive Enhancement & Memory | 1/5 | Animal Only | Status not verified | 45 |
| HumaninMitochondria / cardio-renal | Longevity | Cellular Protection & Metabolic Health | 2/5 | Animal Only | Status not verified | 520 |
| SS-31 (Elamipretide)Mitochondria / cardio-renal | Longevity | Mitochondrial Protection | 3/5 | Human RCT | Status not verified | 340 |
| PinealonBrain / CNS | Cognitive | Neuroprotection & Circadian Regulation | 2/5 | Animal Only | Status not verified | 55 |
| VIPCardiovascular / RAS | Immune | Anti-Inflammatory & Neuroprotection | 3/5 | Human Observational | Status not verified | 4,200 |
| Kisspeptin-10Hormones / reproductive | Metabolic | Reproductive Hormone Regulation | 3/5 | Human RCT | 503A Category 2 | 890 |
| 5-Amino-1MQMetabolism / fat / incretin | Metabolic | Metabolic Optimization & Fat Loss | 1/5 | Animal Only | Status not verified | 35 |
| ArgirelineSkin / connective tissue | Longevity | Topical Anti-Wrinkle (Botox-Like) | 3/5 | Human Observational | Status not verified | 95 |
| CarnosineLongevity / cellular | Longevity | Anti-Aging & Neuroprotection | 3/5 | Human Observational | Status not verified | 1,850 |
| GonadorelinHormones / reproductive | Metabolic | Reproductive Hormone Support | 4/5 | Human RCT | Status not verified | 2,100 |
| OxytocinHormones / reproductive | Cognitive | Social Bonding & Stress Reduction | 4/5 | Human RCT | Status not verified | 6,200 |
| Melanotan IISkin / connective tissue | Metabolic | Tanning & Sexual Function | 2/5 | Human Observational | Nomination withdrawn | 185 |
| Thymosin Beta-4Muscle / tendon / recovery | Recovery | Tissue Repair & Cardiac Protection | 3/5 | Human Observational | Status not verified | 1,031 |
| FOXO4-DRILongevity / cellular | Longevity | Senolytic Therapy | 1/5 | Animal Only | Status not verified | 85 |
| LiraglutideMetabolism / fat / incretin | GLP-1 | GLP-1 Weight & Metabolic Management | 5/5 | Human RCT | Status not verified | 5,800 |
| Snap-8Skin / connective tissue | Longevity | Topical Anti-Wrinkle | 2/5 | Human Observational | Status not verified | 28 |
| Palmitoyl Tripeptide-1Skin / connective tissue | Longevity | Collagen Stimulation & Skin Repair | 3/5 | Human Observational | Status not verified | 120 |
| RapamycinMetabolism / fat / incretin | Longevity | mTOR Inhibition & Longevity | 4/5 | Human RCT | Status not verified | 14,200 |
| MGF (Mechano Growth Factor)Muscle / tendon / recovery | Recovery | Muscle Repair & Satellite Cell Activation | 2/5 | Animal Only | 503A Category 3 | 310 |
| Humanin-G (HNG)Mitochondria / cardio-renal | Longevity | Neuroprotection & Metabolic Protection | 2/5 | Animal Only | Status not verified | 145 |
| Desmopressin (DDAVP)Cardiovascular / RAS | Cognitive | ADH Replacement & Memory Enhancement | 5/5 | Human RCT | Status not verified | 3,800 |
| Angiotensin 1-7Cardiovascular / RAS | Immune | Cardiovascular & Anti-Inflammatory | 3/5 | Human Observational | Status not verified | 2,800 |
| CerebrolysinBrain / CNS | Cognitive | Neuroprotection & Cognitive Recovery | 3/5 | Human RCT | Status not verified | 1,250 |
| Follistatin-344Muscle / tendon / recovery | Recovery | Muscle Growth & Anti-Aging | 2/5 | Animal Only | Status not verified | 580 |
| Pentadeca Arginate (PDA)Gut / repair | Recovery | Recovery Research | 3/5 | Animal Only | Status not verified | 0 |
| PE-22-28Brain / CNS | Cognitive | Cognitive Research | 3/5 | Animal Only | Status not verified | 15 |
| FGL Peptide (NCAM-derived)Brain / CNS | Cognitive | Cognitive Research | 2/5 | Animal Only | Status not verified | 12 |
| Epithalon + Pinealon StackLongevity / cellular | Longevity | Longevity Research | 2/5 | Human Observational | Status not verified | 47 |
| CortagenBrain / CNS | Cognitive | Cognitive Research | 2/5 | Animal Only | Status not verified | 5 |
| VilonImmune / thymus | Immune | Immune Research | 2/5 | Human Observational | Status not verified | 3 |
| ThymulinImmune / thymus | Immune | Immune Research | 3/5 | Human Observational | Status not verified | 839 |
| Thymosin Beta-4 Fragment (TB4-Frag, Ac-LKKTETQ)Muscle / tendon / recovery | Recovery | Recovery Research | 3/5 | Animal Only | Status not verified | 107 |
| GLP-1 (Native/Endogenous)Metabolism / fat / incretin | GLP-1 | GLP-1 Research | 5/5 | Human RCT | Status not verified | 539 |
| Leu-EnkephalinBrain / CNS | Immune | Immune Research | 3/5 | Animal Only | Status not verified | 6,174 |
| Delta-Sleep Inducing Peptide Analogs (DSIP Analogs)Brain / CNS | Cognitive | Cognitive Research | 2/5 | Human Observational | Status not verified | 543 |
| Copper Peptide GHK (Without Copper)Skin / connective tissue | Recovery | Recovery Research | 3/5 | Human Observational | Status not verified | 118 |
| Collagen Peptides (Type I Hydrolysate)Skin / connective tissue | Recovery | Recovery Research | 4/5 | Human RCT | Status not verified | 153 |
| Glutamine Peptide (Alanyl-L-Glutamine)Gut / repair | Recovery | Recovery Research | 4/5 | Human RCT | Status not verified | 89 |
| Larazotide Acetate (AT-1001)Gut / repair | Immune | Immune Research | 3/5 | Human RCT | Status not verified | 106 |
| Ginsenoside Rg3 (RG3)Metabolism / fat / incretin | Immune | Immune Research | 3/5 | Human Observational | Status not verified | 915 |
| ARA-290 (Cibinetide)Cardiovascular / RAS | Immune | Immune Research | 4/5 | Human RCT | Status not verified | 59 |
| BPC-157 Arginate Salt (FDA Regulatory Context)Gut / repair | Recovery | Recovery Research | 2/5 | Animal Only | Status not verified | 212 |
| TriptorelinHormones / reproductive | Metabolic | Metabolic Research | 5/5 | Human RCT | Status not verified | 2,448 |
| Leuprolide (Leuprorelin)Hormones / reproductive | Metabolic | Metabolic Research | 5/5 | Human RCT | Status not verified | 4,156 |
| CetrorelixHormones / reproductive | Metabolic | Metabolic Research | 5/5 | Human RCT | Status not verified | 789 |
| AbaloparatideBone | Recovery | Recovery Research | 5/5 | Human RCT | Status not verified | 382 |
| Teduglutide (GLP-2 Analog)Gut / repair | GLP-1 | GLP-1 Research | 5/5 | Human RCT | Status not verified | 366 |
| MacimorelinHormones / GH axis | Metabolic | Metabolic Research | 5/5 | Human RCT | Status not verified | 44 |
| Afamelanotide (Scenesse)Skin / connective tissue | Immune | Immune Research | 5/5 | Human RCT | Status not verified | 116 |
| CagrilintideMetabolism / fat / incretin | GLP-1 | GLP-1 Research | 4/5 | Human RCT | Status not verified | 72 |
Tissue Repair & Cytoprotection
Cell Migration & Angiogenesis
Collagen Synthesis & Tissue Remodeling
Telomerase Activation & Longevity
Metabolic Resilience & Aging
Growth Hormone Stimulation
Selective GH Secretagogue
Long-Acting Growth Hormone Release
Cellular Energy & Longevity
Immune Modulation & T-Cell Support
GLP-1 Metabolic & Weight Management
Dual GLP-1/GIP Agonist
Triple GLP-1/GIP/Glucagon Agonist
HIV Lipodystrophy & GH Stimulation
Sexual Function & Arousal
Muscle Hypertrophy & Growth Factor Signaling
GH Release & Cardioprotection
Growth Hormone Stimulation
GH Release & Appetite Stimulation
Oral GH Secretagogue
Metabolic & Fat Loss
Antimicrobial & Immune Defense
Gut Inflammation & Immune Modulation
Anxiolytic & Cognitive Enhancement
Neuroprotection & Cognitive Function
Sleep Regulation & Stress Response
Cognitive Enhancement & Memory
Cellular Protection & Metabolic Health
Mitochondrial Protection
Neuroprotection & Circadian Regulation
Anti-Inflammatory & Neuroprotection
Reproductive Hormone Regulation
Metabolic Optimization & Fat Loss
Topical Anti-Wrinkle (Botox-Like)
Anti-Aging & Neuroprotection
Reproductive Hormone Support
Social Bonding & Stress Reduction
Tanning & Sexual Function
Tissue Repair & Cardiac Protection
Senolytic Therapy
GLP-1 Weight & Metabolic Management
Topical Anti-Wrinkle
Collagen Stimulation & Skin Repair
mTOR Inhibition & Longevity
Muscle Repair & Satellite Cell Activation
Neuroprotection & Metabolic Protection
ADH Replacement & Memory Enhancement
Cardiovascular & Anti-Inflammatory
Neuroprotection & Cognitive Recovery
Muscle Growth & Anti-Aging
Recovery Research
Cognitive Research
Cognitive Research
Longevity Research
Cognitive Research
Immune Research
Immune Research
Recovery Research
GLP-1 Research
Immune Research
Cognitive Research
Recovery Research
Recovery Research
Recovery Research
Immune Research
Immune Research
Immune Research
Recovery Research
Metabolic Research
Metabolic Research
Metabolic Research
Recovery Research
GLP-1 Research
Metabolic Research
Immune Research
GLP-1 Research
Added Oct 29, 2026. Each status links its primary source on the compound page.
Educational only. Not medical advice. Research information is not evidence of FDA approval. Approval, where applicable, is specific to a drug product, indication and route. See the medical and editorial disclaimer.