CognitiveApprovedEvidence tier: Human RCT

Desmopressin (DDAVP)

Last updated October 21, 2026. Approval line checked October 21, 2026. No compounding source date is assigned.

FDA status

Approved

Approved. Desmopressin is an FDA-approved drug product for specific indications. Approval is specific to the product, indication, and route.

Drugs@FDA: desmopressin (NDA 017922)

Evidence tier

Human RCT. The tier is the highest indexed study type. It is not a safety rating and it is not an FDA approval. Confidence score 5/5. 3,800 PubMed citations indexed.

Desmopressin (DDAVP) in the literature

Synthetic vasopressin analog with high V2 receptor selectivity; reduces renal water excretion and may enhance memory consolidation via V1 receptor activation in hippocampus.

What the literature studies

ADH Replacement & Memory Enhancement

Evidence tier

Human RCT

Compounding record

Status not verified

Confidence
5/5

Regulatory record

Status not verified. No product-specific FDA primary source is recorded for this entry. FDA approval and compounding eligibility are not verified. Research information is not evidence of FDA approval. Approval, where applicable, is specific to a drug product, indication and route. Research information is not evidence of FDA approval. Approval, where applicable, is specific to a drug product, indication and route.

Regulatory source not verified; no checked date is assigned.

hyponatremia risk, especially in elderly.

Questions

Educational only. Not medical advice. This page does not give doses or sourcing. See the medical and editorial disclaimer.