Is compounded semaglutide still available?

Last checked Nov 2, 2026

Is compounded semaglutide still available?

Generally not as a routine copy of the brand-name drug. The FDA declared the national semaglutide shortage resolved on February 21, 2025, and its grace periods for compounders ended in spring 2025: in late April for state-licensed pharmacies and May 22, 2025 for outsourcing facilities. A pharmacy may still compound a version for an individual patient when a prescriber documents a significant medical difference from the approved drug. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold.

Sources: FDA, Feb 21, 2025; FDA order; FDA on unapproved GLP-1 drugs. See also the GLP-1 cost guide.

Educational info, not medical advice. PeptideX doesn't give dosing advice. Talk to a licensed clinician.